Product Name: Exemestane
Synonyms: Aromasin
CAS: 107868-30-4
MF: C20H24O2
MW: 296.4
mp: 155.13°C
storage temp: Store at -20°C
appearance: white to light yellow crystal powder
Description:
Aromasin is used to fight breast cancer and raise testosterone in the body.
Exemestane blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
Exemestane is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink
It is used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.
1. It is one of the most powerful estrogen suppressing compounds.
2. It is one of the best compounds to lower the aromatizing effect of steroids.
3. It is available for body builders taking anabolic steroids.
4. It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.
5. It is also a kind of antineoplastic (hormonal) raw materials.
Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
Contacts: June & Eason
Whatsapp:+8618206063252; +8618759200098
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Aromasin is used to fight breast cancer and raise testosterone in the body.
Exemestane acetate blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane acetate can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
Most aromatase inhibitors are not steroids in any shape or form but here we must make an exception. Understand, most who buy Aromasin do so because its use with other steroids can often be very important regarding side-effects but Aromasin itself actually carries some androgenic qualities as well. Even so, while possessing an androgenic nature it is its estrogen reducing we are largely concerned with.
the third generation aromatase inhibitors, used in the treatment of metastatic breast cancer and used as aid in the treatment of early breast cancer.
Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.
In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.
Aromasin blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking Aromasin can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
TEST ITEMS | SPECIFICATION | RESULTS |
Description | : White Crystalline Powder | White Powder |
Identification | : Positive | Positive |
Assay(by HPLC) | : 98.0~102.0% | 98.64% |
Absorbance(E1cm) | : 465~495 | 482.5 |
Melting Point | : 191~195°C | 193.5~195.0°C |
Loss On Drying | : 0.5%max | 0.19% |
Specific Rotation | : +288°~ +298° | +290.2° |
Residue On Ignition | : 0.1%max | 0.03% |
Related Substances | : Total:1.5%max | <1.3% |
Single:0.5%max | <0.4% | |
Residue Solvents | : 0.2%max | 0.10% |
Heavy Metals | : 20PPm max | <10PPm |
Conclusion | The specification conform with enterprise standard. |
Exemestane is an irreversible steroid aromatase inhibitor. Its structure is similar to that of aromatase’s natural substrate, androstenedione, and acts as a pseudosubstrate. Postmenopausal women’s estrogen is mainly converted from androgen (produced by the adrenal cortex) by aromatase in the surrounding tissue. This drug irreversibly binds with the active site on aromatase to deactivate it, thus dramatically lower estrogen levels in the blood circulation of postmenopausal women. By inhibiting aromatase to lower estrogen levels, it can be used to treat hormone-dependent breast cancer in postmenopausal women.
Exemestane is suitable for treating advanced breast cancer in naturally or artificially postmenopausal women that has not responded well to tamoxifen treatment. It is also suitable for treating estrogen and progesterone receptor positive postmenopausal advanced breast cancer, and it can also be used to treat metastasized breast cancer and as adjuvant therapy for early breast cancer.
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1. All powders are factory directly supplying.
2. Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
3. Our products are of high quality at competitive prices. Free samples are available.
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5. Flexible and Untraceable payment terms.
6. Exclusive customer service and 24/7 online timely and helpful after-sale service.
1. High purity and good quality.
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4. High success rate to pass customs.
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Strict quality control before products are allowed to sell
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Q1:Can I get some raw steroids samples?
A:Sure,we can supply the free steroids powder sample,just pay shipping cost.
Q2:How to make orders?
A:Please send inquiry to us,after we come to an agreement,send payment via Bitcoin, paypal, bank transfer, Wise Transfer, etcthen we ship products out and give tracking number to you.
Q3:How to delivery?
A:Pack shipped in 2 days(Chinese holiday not included) after payment,usually ship via Fedex,EMS,HKEMS,DHL,TNT,UPS,NL Post,USPS Domestic fast shipping,signature not requested.
Q4:Is there any discount?
A:Yes.The price is negotiable,If you order large quantity or some products together,you will get discount and enjoy free shipping.
Q5:What is the Minimum order quantity?
A:The Min. order quantity according to your request,10g,50g all is OK.
The price is negotiable,it according to the order quantity,the larger the order is,the better the price is.